The mainstream holds subjective cognitive decline (SCD) as more than ten-year latent preclinical stage of Alzheimer′s disease (AD). Due to its normal objective neuropsychological function and the presence of pathological changes in the brain, SCD has been regarded as a key period for the prediction and early intervention of Alzheimer′s disease in recent years. Since pharmacologic interventions in the SCD stage is not applicable, active non-pharmacologic interventions and effective prevention have become the main orientation of the current research. This paper aims to summarize and evaluate the latest research progress of non-pharmacologic interventions in SCD both in China and in other countries to provide effective strategies for AD prevention and treatment clinically.