Research progress in biologic markers for prostate cancer
Received:January 11, 2020  
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DOI:10.11915/j.issn.1671-5403.2021.01.016
Key words:prostate cancer  biomarker  diagnosis This work was supported by Basic Public Welfare Research Project of Zhejiang Provincie
Author NameAffiliationE-mail
ZHOU Pu-Fan Central Laboratory of Molecular Medicine Research Center,Jiaxing 314001, Zhejiang Province, China
Jiaxing Key Laboratory of Diabetic Angiopathy, Jiaxing 314001, Zhejiang Province, China 
shiyanbocas@163.comresearch 
SHEN Rui-Lin Department of Urology Surgery, Jiaxing Second Hospital, Jiaxing 314001, Zhejiang Province, China shiyanbocas@163.comresearch 
XIONG Lie Central Laboratory of Molecular Medicine Research Center,Jiaxing 314001, Zhejiang Province, China
Jiaxing Key Laboratory of Diabetic Angiopathy, Jiaxing 314001, Zhejiang Province, China 
shiyanbocas@163.comresearch 
SHENG Tao Department of Urology Surgery,Jiaxing 314001, Zhejiang Province, China shiyanbocas@163.comresearch 
SONG Bao-Lin Department of Urology Surgery,Jiaxing 314001, Zhejiang Province, China shiyanbocas@163.comresearch 
WANG Xing-Bai Department of Radiology,Jiaxing 314001, Zhejiang Province, China shiyanbocas@163.comresearch 
LU Hai-Juan Department of Ultrasound, Jiaxing Traditional Chinese Medicine Hospital Affiliated to Zhejiang Chinese Medicial University, Jiaxing 314001, Zhejiang Province, China shiyanbocas@163.comresearch 
HUANG Tao Department of Urology Surgery,Jiaxing 314001, Zhejiang Province, China shiyanbocas@163.comresearch 
SHI Han-Qiang Central Laboratory of Molecular Medicine Research Center,Jiaxing 314001, Zhejiang Province, China
Jiaxing Key Laboratory of Diabetic Angiopathy, Jiaxing 314001, Zhejiang Province, China 
shiyanbocas@163.comresearch 
SHAO Huan Department of Urology Surgery,Jiaxing 314001, Zhejiang Province, China shiyanbocas@163.comresearch 
HE Yan-Mei Department of Urology Surgery,Jiaxing 314001, Zhejiang Province, China shiyanbocas@163.comresearch 
WANG Xiao-Ting Department of Urology Surgery,Jiaxing 314001, Zhejiang Province, China shiyanbocas@163.comresearch 
JIANG Da-Wei Department of Urology Surgery,Jiaxing 314001, Zhejiang Province, China shiyanbocas@163.comresearch 
SHI Yan-Bo Central Laboratory of Molecular Medicine Research Center,Jiaxing 314001, Zhejiang Province, China
Jiaxing Key Laboratory of Diabetic Angiopathy, Jiaxing 314001, Zhejiang Province, China 
shiyanbocas@163.comresearch 
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Abstract:
      As one of the most common cancers in men, prostate cancer seriously threatens their health and safety. There are many challenges of prostate cancer in prediction, diagnosis and prognosis. Although biomarkers for the prostate cancer have shown certain clinic significance, they still have limitations when used alone. Accurate diagnosis, prevention of excessive biopsies, and construction of a diagnostic system of combined biomarkers are still trending research topics in the detection of prostate cancer. Here we analyze the cha-llenges in the detection of prostate cancer and review the research progress in biomarkers and related detection systems of prostate cancer.
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