Effect of ultrasound-guided superficial cervical plexus block combined with general anesthesia on postoperative recovery quality and cognitive function in patients undergoing carotid endarterectomy
Received:November 16, 2019  
View Full Text  View/Add Comment  Download reader
DOI:10.11915/j.issn.1671-5403.2020.09.158
Key words:carotid endarterectomy  superficial cervical plexus block  general anesthesia  quality of recovery  cognitive function Corresponding author:CHEN Xiu-Xia, E-mail:cxxlxy@sina.com〖FL
Author NameAffiliationE-mail
WANG Tao Faculty of Anesthesiology, Xuzhou 221004, Jiangsu Province, China cxxlxy@sina.comeffect 
CHEN Xiu-Xia Department of Anesthesiology, Affiliated Hospital, Xuzhou 221004, Jiangsu Province, China cxxlxy@sina.comeffect 
HUANG Jing-Jing Faculty of Anesthesiology, Xuzhou 221004, Jiangsu Province, China cxxlxy@sina.comeffect 
MENG Xiang-Di Faculty of Anesthesiology, Xuzhou 221004, Jiangsu Province, China cxxlxy@sina.comeffect 
LI Xia Faculty of Emergency and Rescue Medicine, Xuzhou Medical University, Xuzhou 221004, Jiangsu Province, China cxxlxy@sina.comeffect 
Hits: 492
Download times: 373
Abstract:
      Objective To compare the effect of ultrasound-guided superficial cervical plexus (SCP) block combined with general anesthesia versus general anesthesia alone on early recovery quality and cognitive function in patients undergoing carotid endarterectomy (CEA). Methods A total of 60 patients undergoing elective CEA in our affiliated hospital from November 2018 to August 2019 were enrolled, and randomly divided into the observation group (ultrasound-guided SCP block combined with general anesthesia) and control group (general anesthesia), with 30 cases in each group. The quality of recovery score (QoR-15), score of mini-mental state examination (MMSE), systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP) and heart rate (HR) were recorded at different time points in both groups. The incidence of adverse events, use of vasoactive drugs and dose of anesthetics were compared between the two groups. SPSS statistics 19.0 was used for data analysis. Student′s t test or Chi-square test was employed for comparison between the two groups. Results The total score of QoR-15 at 1d after surgery was significantly higher in the observation group than the control group [(102.67±10.16) vs (91.87±10.13), P<0.05]. But there were no statistical differences in MMSE scores at different time points between the 2 groups (P>0.05). The observation group had obviously lower SBP[(125.56±9.55) vs (135.86±13.68)mmHg], DBP [(66.92±9.32) vs (76.77±11.73)mmHg], MAP [(86.47±9.02) vs (96.47±11.50)mmHg], and HR [(65.77±6.64) vs (70.50±4.93)beats/min] at moment of incision than the control group (P<0.05). There were notably less patients having hypertension (40.0% vs 70.0%), experiencing nausea and vomiting (13.3% vs 36.7%) and hypoxemia (3.3% vs 23.3%), and using antihypertensive drug (40.0% vs 66.7%) in the observation group than the control group (P<0.05). Less dosages of sufentanil [(0.14±0.03) vs (0.23±0.03)μg/kg], remifentanil [(13.56±2.35) vs (22.13±2.31)μg/kg] and propofol [(7.64±1.04) vs (9.01±1.18)mg/kg] were used in the former than the latter groups (P<0.05).Conclusion For CEA, ultrasound-guided SCP block combined with general anesthesia can improve short-term postoperative QoR-15 score, stabilize perioperative hemodynamics, decrease the dosages of anesthetics and vasoactive drugs, and reduce postoperative adverse events.
Close