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| Research progress in melatonin cardioprotection against ischaemia/reperfusion in jury |
| Received:April 08, 2019 |
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| DOI：10.11915/j.issn.1671-5403.2019.11.182 |
| Key words:receptor, melatonin myocardial ischemia reperfusion injury myocardial protection This work was supported by the Special Research Fund for Military Health Care |
| Author Name | Affiliation | E-mail | | XU Hu | Department of Cardiology, Second Medical Center, Chinese PLA General Hospital, Beijing 100853, China
Second Medical Center, | fl6698@163.comresearch | | FAN Li | Second Medical Center,
National Clinical Research Center for Geriatric Diseases, Chinese PLA General Hospital, Beijing 100853, China | fl6698@163.comresearch | | CAO Feng | Second Medical Center,
National Clinical Research Center for Geriatric Diseases, Chinese PLA General Hospital, Beijing 100853, China
Translational Medicine Center, Chinese PLA General Hospital, Beijing 100853, China | fl6698@163.comresearch |
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| Abstract: |
| Melatonin, a hormone with multiple functions, can activate a vast array of complex signaling pathways by binding specific receptors, thus protecting the heart against ischemia/reperfusion injury. This review summarizes on the melatonin receptors, the probable mechanism of melatonin-induced myocardial protection, and its therapeutic application and clinical research. |
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