Research progress of CYP2C19 genotype with myocardial injury and long-term major adverse cardiovascular events after percutaneous coronary intervention
Received:August 22, 2017  Revised:September 22, 2017
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DOI:10.11915/j.issn.1671-5403.2018.04.070
Key words:genotype  myocardial injury  clopidogrel resistance  percutaneous coronary intervention  major adverse cardiovascular events
Author NameAffiliationE-mail
CHEN Xi Department of Cardiology, First Affiliated Hospital of Harbin Medical University, Harbin 150000, China  
ZHAO Cui Ping Department of Cardiology, First Affiliated Hospital of Harbin Medical University, Harbin 150000, China zhaocuiping2000@163.com 
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Abstract:
      Dual antiplatelet therapy is recommended for coronary heart disease patients after percutaneous coronary intervention (PCI) so as to reduce the risk of major adverse cardiovascular events (MACE). However, some patients do not display adequate antiplatelet response and show resistance to clopidogrel, which seriously affecting the prognosis of them. Therefore, it is a practical problem for the relationship between CYP2C19 genetic polymorphisms and myocardial injury after PCI as well as long-term MACE. We reviewed the problem in this article.
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