|
Exercise-induced myokines and sedentary chronic diseases |
Received:December 29, 2016 Revised:February 16, 2017 |
View Full Text View/Add Comment Download reader |
DOI:10.11915/j.issn.1671-5403.2017.07.130 |
Key words:exercise myokine chronic inflammation sedentary chronic diseases |
|
Hits: 1908 |
Download times: 1112 |
Abstract: |
Exercise can help prevent and treat all of the sedentary chronic diseases such as cancer, diabetes and cardiovascular disease. This may be due to endocrine and paracrine functions of skeletal muscles. Contracted muscles can release some hormones-like myokines, such as interleukin-6 (IL-6), IL-15, brain-derived neurotrophic factor (BDNF) and others. These myokines play roles in organ cross talk, including interactive adjustment among body organs, muscle and fat. Some myokines exert endocrine function, regulate the oxidation of visceral fat or mediate direct anti-inflammatory effects. While, other myokines play roles in fat oxidation-related signal pathway within the skeletal muscles through paracrine mechanism. |
Close |
|
|
|