Comparison of thromboelastography and conventional coagulation tests in critically ill patients
Received:December 29, 2016  Revised:March 24, 2017
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DOI:10.11915/j.issn.1671-5403.2017.07.118
Key words:thromboelastography  conventional coagulation tests  critical illness
Author NameAffiliationE-mail
LI Xiao-Ying Department of Critical Care Medicine, Suzhou Municipal Hospital,Suzhou 215002, China  
HOU Yun-Tian Department of Cardiology, Chinese PLA General Hospital, Beijing 100853, China hyt301@126.com 
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Abstract:
      Objective To investigate the commonness and differences between the parameters of thromboelastography (TEG) and those of conventional coagulation tests in critically ill patients from intensive care unit (ICU). Methods A total of 86 critically ill patients admitted in ICU between August 2014 and May 2017 were enrolled in this study and retrospectively analyzed. The parameters of TEG, such as R and K values, α-angle, maximum amplitude(MA), and the results of prothrombin time (PT), activated partial thromboplastin time (APTT), fibrinogen (FIB), and platelet (PLT) count were calculated. Fisher exact test and Kappa identity test were performed. Results The medians of PT and APTT in the patients were higher, while that of PLT was lower than the normal ranges, and those of FIB and TEG were in the normal ranges. Fisher exact test indicated there were significant differences among R value with PT and APTT, K value with APTT, FIB and PLT,α-angle with PT, APTT, FIB and PLT, MA with FIB and PLT (P<0.05). Kappa identity test showed that the correlation was weak between the TEG parameters and the results of conventional coagulation test. Conclusion The consistency is weak between TEG and conventional coagulation test in the critically ill patients from ICU. So, the 2 methods can’t replace each other.
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