Percutaneous coronary intervention (PCI) is an effective treatment for coronary heart disease, but myocardial injury and even myocardial infarction (MI) commonly happened after PCI, which severely influence the curative effect and prognosis of the patients. Therefore, it is a clinical practical problem concerning the causes, diagnosis and prevention of myocardial injury after PCI, which is worth of further discussion. In this article, we reviewed the above mentioned issues.