Anthracycline-induced cardiomyopathy in cancer therapy:one case report and literature review
Received:September 22, 2016  Revised:October 17, 2016
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DOI:10.11915/j.issn.1671-5403.2017.01.014
Key words:anthracyclines  anti-tumortherapy  cardiotoxicity  cardiomyopathy
Author NameAffiliationE-mail
LIN Ying Department of Cardiology, Chinese PLA General Hospital, Beijing 100853, China
Department of Cardiology, Hainan Branch of Chinese PLA General Hospital, Sanya 572013, China 
wy276532635@163.comanthracycline 
LI Yan-Hua Department of Cardiology, Chinese PLA General Hospital, Beijing 100853, China wy276532635@163.comanthracycline 
GUO Xin-Hong Department of Cardiology, Chinese PLA General Hospital, Beijing 100853, China wy276532635@163.comanthracycline 
XU Yong Department of Cardiology, Chinese PLA General Hospital, Beijing 100853, China wy276532635@163.comanthracycline 
LI Yu-Feng Department of Cardiology, Chinese PLA General Hospital, Beijing 100853, China wy276532635@163.comanthracycline 
LIU Yu-Qi Department of Cardiology, Chinese PLA General Hospital, Beijing 100853, China wy276532635@163.comanthracycline 
JIN Rong-Jie Department of Cardiology, Chinese PLA General Hospital, Beijing 100853, China wy276532635@163.comanthracycline 
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Abstract:
      We retrospectively analyzed a particular case of dilated cardiomyopathy, that is,a 65-year-old woman who had no history of heart disease mainly presenting chest tightness and shortness of breath. Related examinations suggested dilated cardiomyopathy, and the patient had ever received anthracycline drugs for breast cancer treatment. We reviewed related literatures and summarized the experience on diagnosis and treatment of anthracycline-induced cardiomyopathy. After standardized and individualized treatment, her symptoms were relieved. Therefore, we should monitor cardiac function during anthracyclines administration to prevent and treat cardiac toxicity caused by chemotherapy drugs. If the condition developes into chronic heart disease, the drugs to improve myocardial prognosis should be used as early as possible.
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