Research progress of blood glucose fluctuation and vascular complications in aged patients with diabetes mellitus
Received:April 25, 2016  
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DOI:10.11915/j.issn.1671-5403.2016.10.189
Key words:blood glucose fluctuation  aged  diabetes mellitus  vascular complications
Author NameAffiliationE-mail
DUAN Jian-Fang, JIN Feng-Zhong, WANG Xiao-Ming, SU Hui* Department of Geriatrics, Xijing Hospital, Fourth Military Medical University, Xi’an 710032, China huisu2014@163.com 
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Abstract:
      Intensive glucose control can reduce the risk of microvascular and macrovascular complications in the patients with early type 2 diabetes mellitus (T2DM). However, elderly patients are characterized by being accompanied with multiple organ dysfunctions, coexistence of various diseases, complexity of medications, large fluctuations in blood glucose, and frequent hypoglycemia. Both excessive glucose fluctuations and severe hypoglycemia are closely associated with vascular complications. So a new treatment concept for the aged T2DM patients is that, on the basis of blood glucose controlling, we should reduce blood glucose fluctuation and occurrence of severe hypoglycemia, and thus, will reduce the occurrence and the development of chronic complications of T2DM.
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