Percutaneous coronary intervention for unprotected left main coronary artery disease in old females: a long-term study on clinical efficiency
  
View Full Text  View/Add Comment  Download reader
DOI:10.3724/SP.J.1264.2014.00094
Key words:coronary artery disease  left main coronary artery  percutaneous coronary intervention  female  aged
Author NameAffiliationE-mail
LIU Hai-Wei, HAN Ya-Ling*, WANG Xiao-Zeng, MA Ying-Yan, JIN Quan-Min, WANG Geng, WANG Bin, XU Kai, ZHAO Xin, GUAN Shao-Yi Department of Cardiology, Shenyang General Hospital, Shenyang Military Command, Shenyang 110084, China hanyaling@126.net 
Hits: 1588
Download times: 1271
Abstract:
      Objective To investigate the long-term outcomes of percutaneous coronary intervention (PCI) in the old female patients with left main coronary artery (LMCA) disease. Methods A total of 302 female patients with LMCA disease who underwent PCI in our department from December 1997 to October 2012 were enrolled and retrospectively analyzed in this study. They were divided into the old group [≥65 years, with age of (72.0±4.31) years, n=156] and non-old group [<65 years, with age of (55.5±7.06) years, n=146]. The time of follow-up was (42.0±19.3) months in both groups after successful angioplasty. The basic clinical and angiographic characteristics, immediate results of PCI and major adverse cardiac event (MACE) defined as target vessel revascularization, acute myocardial infarction, and sudden cardiac death were analyzed between 2 groups during follow-up. Results The ratio of patients with hypertension and acute myocardial infarction were higher in old group than in non-old group, but with no significant difference between them (P>0.05). Compared with non-old group, the Syntax score of the old group was significantly higher [(26.6±8.49) vs (23.5±9.10), P<0.01]. All procedures were successfully completed in all-patients in both groups. The procedural strategies, the length and diameter of stent in LMCA and the ratio of drug eluting stent implantation were not significantly different between two groups. Meanwhile, the rate of MACE, stent thrombosis and all cause death were not significantly different between two groups. Conclusion PCI can be performed in old female LMCA patients successfully and safely. Anti-platelet therapy and optimized procedures will improve the long-term clinical outcomes of PCI in old females with LMCA disease.
Close