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Relationship of hyperuricemia with diabetes and its vascular complications |
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DOI:10.3724/SP.J.1264.2013.00219 |
Key words:hyperuricemia diabetes mellitus diabetic vascular complications |
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Abstract: |
Hyperuricemia has a close correlation with diabetes, and also participates in the incidence and development of diabetic cardiovascular diseases and nephropathy. Hyperuricemia is involved in the pathogenesis of diabetes mainly through insulin resistance, and also contributes to the occurrence of diabetic cardiovascular diseases and nephropathy by endothelial dysfunction and inflammatory cascade reaction. This review mainly elucidates the prevalence and possible mechanism of diabetes and its vascular complications caused by hyperuricemia. |
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