Relationship of hyperuricemia with diabetes and its vascular complications
  
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DOI:10.3724/SP.J.1264.2013.00219
Key words:hyperuricemia  diabetes mellitus  diabetic vascular complications
Author NameAffiliationE-mail
SUN Xue, JIA Wei-Ping, HU Cheng* Department of Endocrinology and Metabolism, Shanghai Diabetes Institute, Shanghai Clinical Center for Diabetes, Affiliated Sixth People’s Hospital, Shanghai Jiaotong University, Shanghai 200233, China alfredhc@sjtu.edu.cn 
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Abstract:
      Hyperuricemia has a close correlation with diabetes, and also participates in the incidence and development of diabetic cardiovascular diseases and nephropathy. Hyperuricemia is involved in the pathogenesis of diabetes mainly through insulin resistance, and also contributes to the occurrence of diabetic cardiovascular diseases and nephropathy by endothelial dysfunction and inflammatory cascade reaction. This review mainly elucidates the prevalence and possible mechanism of diabetes and its vascular complications caused by hyperuricemia.
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