Correlation of brachial ankle pulse wave velocity with cardiovascular risks and Framingham score
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    Abstract:

    Objective To study the relationship of brachial ankle pulse wave velocity(baPWV) with cardiovascular risks and Framingham score, and to estimate the predictive value of baPWV in cardiovascular events. Methods Totally 144 subjects were enrolled and divided into coronary heart disease group (48 cases), non-CHD with cardiovascular risk group (50 cases) and non-CHD without cardiovascular risk group (46 cases). baPWV was detected by artery stiffness testing measurement equipment. Results There was significant difference in baPWV among three groups (P<0.01). After adjusting age, the difference in baPWV between the three groups was still significant(P<0.05). baPWV was positively correlated with conventional cardiovascular risks. Moreover, age and systolic blood pressure were independent indicators of baPWV. baPWV was also positively correlated with Framingham risk score. The predictive value of baPWV was reviewed by using receiver operating characteristic (ROC) curve. Area under ROC curve was 0.768 in CHD group and 0.944 in CHD high-risk group. Conclusion There is good relationship between baPWV and cardiovascular risk factors, and the value of baPWV is moderate in predicting CHD and high in screening population with high risk stratification of CHD.

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