Pathogen distribution and drug resistance in elderly diabetic patients with urinary tract infection
  
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DOI:10.3724/SP.J.1264.2012.00207
Key words:elderly  diabetes mellitus  urinary tract infection  drug sensitivity assay, microbial
Author NameAffiliationE-mail
LIU Wei First Department of Internal Medicine, Guangdong Border Armed Police Corps Hospital, Shenzhen 518029, China lwzat@yahoo.com.cn 
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Abstract:
      Objective To investigate the pathogen distribution and drug resistance in elderly diabetic patients with urinary tract infection. Methods Seventy bacteria strains isolated from the midstream urine of elderly diabetic patients with urinary tract infection were statistically analyzed by pathogens cultivation and drug resistance. Results Among 70 bacteria strains, Gram negative bacteria accounted for 65.7%, Gram positive bacteria accounted for 21.4% and fungi accounted for 12.9%. Escherichia coli was the predominant pathogen among the Gram negative bacteria; while Staphylococcus haemolyticus was the predominant pathogen among the Gram positive bacteria. The Enterococci resistant to Vancomycin was not found. Monilia albicans was the predominant pathogen among fungi. The Gram negative bacteria were sensitive to the following antibiotics: Meropenem, Imipenem, Cefepime, Amikacin and Piperacillin/Tazobactam. Among the Gram positive bacteria, Staphylococcus haemolyticus was sensitive to the following antibiotics: Fusidic acid, Rifampicin, Minocycline, Teicoplanin, Vancomycin, Nitrofurantoin and Quinupristin/Dalfopistin; while Enterococcus faecalis and Enterococcus Faecium were just sensitive to Teicoplanin and Vancomycin. Monilia albicans was sensitive to Fluconazol and Itraconazole. Conclusion Gram negative bacteria were the predominant pathogens in elderly diabetic patients with urinary tract infection. Because of the high antibiotic resistance, it is important to perform urine bacterial culture and drug susceptibility tests in time.
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