Objective To analyze retrospectively clinical curative effect of partly reduction and intervertebral fusion on stable degenerative lumbar spondylolisthesis. Methods A retrospective follow-up analysis included 17 patients with L4-L5 stable lumbar degenerative spondylolisthesis receiving partly reduction and intervertebral fusion treatment from May 2008 to August 2011. Visual analog score(VAS) of back pain and leg pain before and after operation were compared. The lumbar 4 was found slipped in all patients and lumbar hyperextension and hyperflexion X-ray files showed no evidence of lumbar instability. All patients were followed up in 6-12months after operation. Results There was no nail or rod broken, and intervertebral fusion rate was 94%. VAS of low back pain and leg pain were significantly decreased post-operatively(P＜0.01). Conclusion Short-term clinical outcome of partly reduction and intervertebral fusion for treatment of stable degenerative lumbar spondylolisthesis is satisfactory.