Post-stroke cognitive impairment is common in stroke patients, with the incidence of 21.8%~50.0%. Post-stroke cognitive impairment can be burdensome to the involved individuals, as well as to their family members and the society as a whole. But after the acute stage, the patients have different outcome. The patients who are young and have good cognitive condition before stroke usually demonstrate improved cognition after acute stage; while the patients who are older and have poor cognitive condition before stroke, less education, lower blood pressure, severe myelinopathy and diabetes mellitus, usually had depraved cognition after acute stage. There are still some arguments about the effects of gender, stroke location and stroke risk factors including hypertension, hyperlipidemia, heart disease history and alcohol drinking history on the outcome of post-stroke cognitive impairment.